BDBM320292 5-[3-(Dimethyl-1H-1,2,3-triazol-5-yl)-5-[(S)-oxan-4-yl(phenyl)methyl]-5H-pyrido[3,2-b]indol-7-yl]-5-methyl-1,3-oxazolidin-2-one::US10174024, Example 10::US10174024, Example 9

SMILES: Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(ccc21)C1(C)CNC(=O)O1

InChI Key: InChIKey=OYGRLSWYESFYNK-FDOABKJOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 320292   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM320292 (5-[3-(Dimethyl-1H-1,2,3-triazol-5-yl)-5-[(S)-oxan-...) Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(ccc21)C1(C)CNC(=O)O1 |r| Show InChI InChI=1S/C31H32N6O3/c1-19-28(36(3)35-34-19)22-15-26-27(32-17-22)24-10-9-23(31(2)18-33-30(38)40-31)16-25(24)37(26)29(20-7-5-4-6-8-20)21-11-13-39-14-12-21/h4-10,15-17,21,29H,11-14,18H2,1-3H3,(H,33,38)/t29-,31?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10174024 (2019) BindingDB Entry DOI: 10.7270/Q2319XZ1
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM320292 (5-[3-(Dimethyl-1H-1,2,3-triazol-5-yl)-5-[(S)-oxan-...) Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(ccc21)C1(C)CNC(=O)O1 |r| Show InChI InChI=1S/C31H32N6O3/c1-19-28(36(3)35-34-19)22-15-26-27(32-17-22)24-10-9-23(31(2)18-33-30(38)40-31)16-25(24)37(26)29(20-7-5-4-6-8-20)21-11-13-39-14-12-21/h4-10,15-17,21,29H,11-14,18H2,1-3H3,(H,33,38)/t29-,31?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10174024 (2019) BindingDB Entry DOI: 10.7270/Q2319XZ1
					More data for this Ligand-Target Pair