BDBM320312 4-(2H3)Methoxy-5-{7-[4-(2H)methoxy-1-methyl-1H-1,2,3-triazol-5-yl]-5-[(S)-oxan-4-yl-(phenyl)methyl]-5H-pyrido[3,2-b]indol-3-yl}-1-methyl-1H-1,2,3-triazole::BDBM320313::US10174024, Example 29

SMILES: COc1nnn(C)c1-c1ccc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(cnc21)-c1c(OC)nnn1C

InChI Key: InChIKey=UQWOIUCJNKEQBG-HHHXNRCGSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 320312   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM320312 (4-(2H3)Methoxy-5-{7-[4-(2H)methoxy-1-methyl-1H-1,2...) Show SMILES COc1nnn(C)c1-c1ccc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(cnc21)-c1c(OC)nnn1C |r| Show InChI InChI=1S/C31H32N8O3/c1-37-28(30(40-3)33-35-37)21-10-11-23-24(16-21)39(27(19-8-6-5-7-9-19)20-12-14-42-15-13-20)25-17-22(18-32-26(23)25)29-31(41-4)34-36-38(29)2/h5-11,16-18,20,27H,12-15H2,1-4H3/t27-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10174024 (2019) BindingDB Entry DOI: 10.7270/Q2319XZ1
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM320312 (4-(2H3)Methoxy-5-{7-[4-(2H)methoxy-1-methyl-1H-1,2...) Show SMILES COc1nnn(C)c1-c1ccc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(cnc21)-c1c(OC)nnn1C |r| Show InChI InChI=1S/C31H32N8O3/c1-37-28(30(40-3)33-35-37)21-10-11-23-24(16-21)39(27(19-8-6-5-7-9-19)20-12-14-42-15-13-20)25-17-22(18-32-26(23)25)29-31(41-4)34-36-38(29)2/h5-11,16-18,20,27H,12-15H2,1-4H3/t27-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10174024 (2019) BindingDB Entry DOI: 10.7270/Q2319XZ1
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM320312 (4-(2H3)Methoxy-5-{7-[4-(2H)methoxy-1-methyl-1H-1,2...) Show SMILES COc1nnn(C)c1-c1ccc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(cnc21)-c1c(OC)nnn1C |r| Show InChI InChI=1S/C31H32N8O3/c1-37-28(30(40-3)33-35-37)21-10-11-23-24(16-21)39(27(19-8-6-5-7-9-19)20-12-14-42-15-13-20)25-17-22(18-32-26(23)25)29-31(41-4)34-36-38(29)2/h5-11,16-18,20,27H,12-15H2,1-4H3/t27-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10174024 (2019) BindingDB Entry DOI: 10.7270/Q2319XZ1
					More data for this Ligand-Target Pair