BDBM320317 2-{5-[(S)-(2-Fluorophenyl)(oxan-4-yl)methyl]-6-methanesulfonyl-3-[4-(2H3)methyl-1-methyl-1H-1,2,3-triazol-5-yl]-5H-pyrido[3,2-b]indol-9-yl}-1λ6,2-thiazolidine-1,1-dione::US10174024, Example 34::US10174024, Example 37

SMILES: Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1F)c1c(ccc(N3CCCS3(=O)=O)c21)S(C)(=O)=O

InChI Key: InChIKey=OKFPOIRULBBXCN-PMERELPUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 320317   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM320317 (2-{5-[(S)-(2-Fluorophenyl)(oxan-4-yl)methyl]-6-met...) Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1F)c1c(ccc(N3CCCS3(=O)=O)c21)S(C)(=O)=O |r| Show InChI InChI=1S/C31H33FN6O5S2/c1-19-29(36(2)35-34-19)21-17-25-28(33-18-21)27-24(37-13-6-16-45(37,41)42)9-10-26(44(3,39)40)31(27)38(25)30(20-11-14-43-15-12-20)22-7-4-5-8-23(22)32/h4-5,7-10,17-18,20,30H,6,11-16H2,1-3H3/t30-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10174024 (2019) BindingDB Entry DOI: 10.7270/Q2319XZ1
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM320317 (2-{5-[(S)-(2-Fluorophenyl)(oxan-4-yl)methyl]-6-met...) Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1F)c1c(ccc(N3CCCS3(=O)=O)c21)S(C)(=O)=O |r| Show InChI InChI=1S/C31H33FN6O5S2/c1-19-29(36(2)35-34-19)21-17-25-28(33-18-21)27-24(37-13-6-16-45(37,41)42)9-10-26(44(3,39)40)31(27)38(25)30(20-11-14-43-15-12-20)22-7-4-5-8-23(22)32/h4-5,7-10,17-18,20,30H,6,11-16H2,1-3H3/t30-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10174024 (2019) BindingDB Entry DOI: 10.7270/Q2319XZ1
					More data for this Ligand-Target Pair