BDBM320318 2-{5-[(3-Fluoropyridin-2-yl)(oxan-4-yl)methyl]-6-methanesulfonyl-3-[4-(2H3)methyl-1-methyl-1H-1,2,3-triazol-5-yl]-5H-pyrido[3,2-b]indol-9-yl}-1λ6,2-thiazolidine-1,1-dione::US10174024, Example 35::US10174024, Example 36

SMILES: Cc1[nH]nn(C)c1-c1cnc2c(c1)n(C(C1CCOCC1)c1ncccc1F)c1c(ccc(N3CCCS3(=O)=O)c21)S(C)(=O)=O

InChI Key: InChIKey=RTZAWQZDUBTVBH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 320318   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM320318 (2-{5-[(3-Fluoropyridin-2-yl)(oxan-4-yl)methyl]-6-m...) Show SMILES Cc1[nH]nn(C)c1-c1cnc2c(c1)n(C(C1CCOCC1)c1ncccc1F)c1c(ccc(N3CCCS3(=O)=O)c21)S(C)(=O)=O Show InChI InChI=1S/C30H32FN7O5S2/c1-18-28(36(2)35-34-18)20-16-23-27(33-17-20)25-22(37-12-5-15-45(37,41)42)7-8-24(44(3,39)40)30(25)38(23)29(19-9-13-43-14-10-19)26-21(31)6-4-11-32-26/h4,6-8,11,16-17,19,29H,5,9-10,12-15H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10174024 (2019) BindingDB Entry DOI: 10.7270/Q2319XZ1
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM320318 (2-{5-[(3-Fluoropyridin-2-yl)(oxan-4-yl)methyl]-6-m...) Show SMILES Cc1[nH]nn(C)c1-c1cnc2c(c1)n(C(C1CCOCC1)c1ncccc1F)c1c(ccc(N3CCCS3(=O)=O)c21)S(C)(=O)=O Show InChI InChI=1S/C30H32FN7O5S2/c1-18-28(36(2)35-34-18)20-16-23-27(33-17-20)25-22(37-12-5-15-45(37,41)42)7-8-24(44(3,39)40)30(25)38(23)29(19-9-13-43-14-10-19)26-21(31)6-4-11-32-26/h4,6-8,11,16-17,19,29H,5,9-10,12-15H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10174024 (2019) BindingDB Entry DOI: 10.7270/Q2319XZ1
					More data for this Ligand-Target Pair