BDBM320327 4-[3-(Dimethyl-1H-1,2,3-triazol-5-yl)-5-[(S)-oxan-4-yl(phenyl)methyl]-5H-pyrido[3,2-b]-indol-7-yl]-1λ6-thiomorpholine-1,1-dione::BDBM320328::US10174024, Example 44

SMILES: Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(ccc21)N1CCS(=O)(=O)CC1

InChI Key: InChIKey=OCFMGXWVDNADHM-WJOKGBTCSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 320327   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM320327 (4-[3-(Dimethyl-1H-1,2,3-triazol-5-yl)-5-[(S)-oxan-...) Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(ccc21)N1CCS(=O)(=O)CC1 |r| Show InChI InChI=1S/C31H34N6O3S/c1-21-30(35(2)34-33-21)24-18-28-29(32-20-24)26-9-8-25(36-12-16-41(38,39)17-13-36)19-27(26)37(28)31(22-6-4-3-5-7-22)23-10-14-40-15-11-23/h3-9,18-20,23,31H,10-17H2,1-2H3/t31-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10174024 (2019) BindingDB Entry DOI: 10.7270/Q2319XZ1
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM320327 (4-[3-(Dimethyl-1H-1,2,3-triazol-5-yl)-5-[(S)-oxan-...) Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(ccc21)N1CCS(=O)(=O)CC1 |r| Show InChI InChI=1S/C31H34N6O3S/c1-21-30(35(2)34-33-21)24-18-28-29(32-20-24)26-9-8-25(36-12-16-41(38,39)17-13-36)19-27(26)37(28)31(22-6-4-3-5-7-22)23-10-14-40-15-11-23/h3-9,18-20,23,31H,10-17H2,1-2H3/t31-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10174024 (2019) BindingDB Entry DOI: 10.7270/Q2319XZ1
					More data for this Ligand-Target Pair