null

SMILES: C=CS(=O)(=O)N[C@H]1CC[C@@H](CC1)NC(=O)c1cc(on1)C1CC1

InChI Key: InChIKey=QVDFJBYGHPQTNP-HAQNSBGRSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 321288   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase SMYD3 (Homo sapiens (Human))	BDBM321288 (5-cyclopropyl-N-((1r,4r)-4- (vinylsulfonamido)cycl...) Show SMILES C=CS(=O)(=O)N[C@H]1CC[C@@H](CC1)NC(=O)c1cc(on1)C1CC1 |r,wU:6.5,wD:9.12,(-8.62,1.5,;-7.29,.73,;-5.96,1.5,;-6.73,2.83,;-5.19,.16,;-4.62,2.27,;-3.29,1.5,;-1.95,2.27,;-.62,1.5,;-.62,-.04,;-1.95,-.81,;-3.29,-.04,;.71,-.81,;2.05,-.04,;2.05,1.5,;3.38,-.81,;4.84,-.34,;5.75,-1.58,;4.84,-2.83,;3.38,-2.35,;7.29,-1.58,;8.62,-.81,;8.62,-2.35,)| Show InChI InChI=1S/C15H21N3O4S/c1-2-23(20,21)18-12-7-5-11(6-8-12)16-15(19)13-9-14(22-17-13)10-3-4-10/h2,9-12,18H,1,3-8H2,(H,16,19)/t11-,12-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
EPIZYME, INC. US Patent					Assay Description The assays were an performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use. ...				US Patent US10669243 (2020)
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase SMYD3 (Homo sapiens (Human))	BDBM321288 (5-cyclopropyl-N-((1r,4r)-4- (vinylsulfonamido)cycl...) Show SMILES C=CS(=O)(=O)N[C@H]1CC[C@@H](CC1)NC(=O)c1cc(on1)C1CC1 |r,wU:6.5,wD:9.12,(-8.62,1.5,;-7.29,.73,;-5.96,1.5,;-6.73,2.83,;-5.19,.16,;-4.62,2.27,;-3.29,1.5,;-1.95,2.27,;-.62,1.5,;-.62,-.04,;-1.95,-.81,;-3.29,-.04,;.71,-.81,;2.05,-.04,;2.05,1.5,;3.38,-.81,;4.84,-.34,;5.75,-1.58,;4.84,-2.83,;3.38,-2.35,;7.29,-1.58,;8.62,-.81,;8.62,-2.35,)| Show InChI InChI=1S/C15H21N3O4S/c1-2-23(20,21)18-12-7-5-11(6-8-12)16-15(19)13-9-14(22-17-13)10-3-4-10/h2,9-12,18H,1,3-8H2,(H,16,19)/t11-,12-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
EPIZYME, INC. US Patent					Assay Description The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....				US Patent US10179773 (2019) BindingDB Entry DOI: 10.7270/Q2DB83ZM
					More data for this Ligand-Target Pair