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SMILES: C\C=C\Cn1cc(-c2ccc(C(=O)N3CCOCC3)c(OC(C)C)c2)c2cc(C)[nH]c2c1=O

InChI Key: InChIKey=SOPWRLFWKSWOGG-AATRIKPKSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321430   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 9 [134-239]


(Homo sapiens (Human))		BDBM321430
PNG
(6-[(E)-but-2-enyl]-4-[3-isopropoxy-4-(morpholine-4...)
Show SMILES C\C=C\Cn1cc(-c2ccc(C(=O)N3CCOCC3)c(OC(C)C)c2)c2cc(C)[nH]c2c1=O
Show InChI InChI=1S/C26H31N3O4/c1-5-6-9-29-16-22(21-14-18(4)27-24(21)26(29)31)19-7-8-20(23(15-19)33-17(2)3)25(30)28-10-12-32-13-11-28/h5-8,14-17,27H,9-13H2,1-4H3/b6-5+
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 3n/an/an/an/an/an/a



GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent


Assay Description
His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...

US Patent US10183009 (2019)


BindingDB Entry DOI: 10.7270/Q2125VRQ
More data for this
Ligand-Target Pair