BDBM322449 (R)-2-methyl-N-(1'-azaspiro[cyclopropane-1,2'-bicyclo[2.2.2]octan]-3'-yl)benzo[b]thiophene-6-carboxamide-hydrochloride::US10183938, Compound (R)-202

SMILES: Cc1cc2ccc(cc2s1)C(=O)N[C@@H]1C2CCN(CC2)C11CC1

InChI Key: InChIKey=VOCFPFPMGLTSHF-QGZVFWFLSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 322449   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-7 subunit (Homo sapiens (Human))	BDBM322449 ((R)-2-methyl-N-(1'-azaspiro[cyclopropane-1,2'-bicy...) Show SMILES Cc1cc2ccc(cc2s1)C(=O)N[C@@H]1C2CCN(CC2)C11CC1 Show InChI InChI=1S/C19H22N2OS/c1-12-10-14-2-3-15(11-16(14)23-12)18(22)20-17-13-4-8-21(9-5-13)19(17)6-7-19/h2-3,10-11,13,17H,4-9H2,1H3,(H,20,22)/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axovant Sciences GmbH US Patent					Assay Description The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...				US Patent US10183938 (2019) BindingDB Entry DOI: 10.7270/Q2VD71JR
					More data for this Ligand-Target Pair