BDBM323223 N-[(R)-1-(3,4-difluorobenzyl)-2-oxo-2-(3-pentyl-3-phenylazetidin-1-yl)ethyl]-3-(1H-imidazol-4-yl)propionamide::US9630949, 53

SMILES: CCCCCC1(CN(C1)C(=O)[C@@H](Cc1ccc(F)c(F)c1)NC(=O)CCc1c[nH]cn1)c1ccccc1

InChI Key: InChIKey=QWHKKXUZOHOJBP-AREMUKBSSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323223   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM323223 (N-[(R)-1-(3,4-difluorobenzyl)-2-oxo-2-(3-pentyl-3-...) Show SMILES CCCCCC1(CN(C1)C(=O)[C@@H](Cc1ccc(F)c(F)c1)NC(=O)CCc1c[nH]cn1)c1ccccc1 Show InChI InChI=1S/C29H34F2N4O2/c1-2-3-7-14-29(22-8-5-4-6-9-22)18-35(19-29)28(37)26(16-21-10-12-24(30)25(31)15-21)34-27(36)13-11-23-17-32-20-33-23/h4-6,8-10,12,15,17,20,26H,2-3,7,11,13-14,16,18-19H2,1H3,(H,32,33)(H,34,36)/t26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description In the presence of an activator (agonist), the melanocortin receptor will activate the cAMP pathway which, via the CRE-Luc vector, will result in the...				US Patent US9630949 (2017) BindingDB Entry DOI: 10.7270/Q21Z46H9
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM323223 (N-[(R)-1-(3,4-difluorobenzyl)-2-oxo-2-(3-pentyl-3-...) Show SMILES CCCCCC1(CN(C1)C(=O)[C@@H](Cc1ccc(F)c(F)c1)NC(=O)CCc1c[nH]cn1)c1ccccc1 Show InChI InChI=1S/C29H34F2N4O2/c1-2-3-7-14-29(22-8-5-4-6-9-22)18-35(19-29)28(37)26(16-21-10-12-24(30)25(31)15-21)34-27(36)13-11-23-17-32-20-33-23/h4-6,8-10,12,15,17,20,26H,2-3,7,11,13-14,16,18-19H2,1H3,(H,32,33)(H,34,36)/t26-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description In the presence of an activator (agonist), the melanocortin receptor will activate the cAMP pathway which, via the CRE-Luc vector, will result in the...				US Patent US9630949 (2017) BindingDB Entry DOI: 10.7270/Q21Z46H9
					More data for this Ligand-Target Pair