BindingDB PrimarySearch

null

SMILES: COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1

InChI Key: InChIKey=MYQAUKPBNJWPIE-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 801 hits for monomerid = 32362
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Calcium/calmodulin-dependent protein kinase type IV (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for CAMK4 kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase kinase 1 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for CAMKK1 kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Ephrin type-A receptor 1 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for EPHA1 kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Ephrin type-A receptor 2 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for EPHA2 kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for MERTK kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for FLT1 kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 12 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for full-length p38-gamma				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 2 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for full-length MEK2				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 3 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for full-length MEK3				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Casein kinase I isoform gamma-2 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for full-length CSNK1G2				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase HCK (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for HCK kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for IGF1R kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 4 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for MEK4 kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for CAMK2D kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for AURKA kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for PDGFRA kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for PDGFRB kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Casein kinase I isoform gamma-1 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for CSNK1G1 kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 32C (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for YANK3 kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for EPHA4 kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 5 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for PAK7/PAK5 kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase ZAP-70 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for ZAP70 kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Ephrin type-B receptor 1 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for EPHB1 kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for RET(M918T) kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for RIPK1 kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase LATS2 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for LATS2 kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for full-length CDK5				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D3 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for PRKD3 kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for DRAK1 kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for JNK3 kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for full-length JNK2				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
LIM domain kinase 1 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for full-length LIMK1				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for AMPK-alpha1 kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 16 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for PCTK1 kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 6 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for MEK6 kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase ROS (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for ROS1 kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for TXK kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 11A (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for CDC2L2 kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for RPS6KA3(Kin.Dom.1 - N-terminal) kinase domain				Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2
Ambit Biosciences Curated by ChEMBL					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
University of the Pacific Curated by ChEMBL					Assay Description Binding affinity to human KIT incubated for 1 hr by kinase binding assay				Eur J Med Chem 46: 2043-57 (2011) Article DOI: 10.1016/j.ejmech.2011.02.057 BindingDB Entry DOI: 10.7270/Q2F47Q45
University of the Pacific Curated by ChEMBL					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	148	n/a	n/a	n/a	n/a	n/a	n/a
University of Sharjah Curated by ChEMBL					Assay Description Inhibition of CSF1R in human monocytes assessed as inhibition of CSF1-stimulated MCP release				J Med Chem 61: 5450-5466 (2018) Article DOI: 10.1021/acs.jmedchem.7b00873 BindingDB Entry DOI: 10.7270/Q2P55R5S
University of Sharjah Curated by ChEMBL					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
University of Sharjah Curated by ChEMBL					Assay Description Inhibition of CSF1R (unknown origin)				J Med Chem 61: 5450-5466 (2018) Article DOI: 10.1021/acs.jmedchem.7b00873 BindingDB Entry DOI: 10.7270/Q2P55R5S
University of Sharjah Curated by ChEMBL					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
University of Sharjah Curated by ChEMBL					Assay Description Inhibition of CSF1R in human monocytes assessed as inhibition of IL34-stimulated MCP release				J Med Chem 61: 5450-5466 (2018) Article DOI: 10.1021/acs.jmedchem.7b00873 BindingDB Entry DOI: 10.7270/Q2P55R5S
University of Sharjah Curated by ChEMBL					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Chung-Ang University Curated by ChEMBL					Assay Description Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...				Bioorg Med Chem Lett 29: 271-275 (2019) Article DOI: 10.1016/j.bmcl.2018.11.037 BindingDB Entry DOI: 10.7270/Q2QJ7MN8
Chung-Ang University Curated by ChEMBL					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
University of Arkansas for Medical Sciences Curated by ChEMBL					Assay Description Inhibition of TRKA (unknown origin) by ATP site-dependent competition binding assay				J Med Chem 62: 1731-1760 (2019) Article DOI: 10.1021/acs.jmedchem.8b01092 BindingDB Entry DOI: 10.7270/Q29Z986G
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
University of Arkansas for Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human CSF1R catalytic domain by ATP-based kinase assay				J Med Chem 62: 1731-1760 (2019) Article DOI: 10.1021/acs.jmedchem.8b01092 BindingDB Entry DOI: 10.7270/Q29Z986G
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CSF1R (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00936 BindingDB Entry DOI: 10.7270/Q2Q81HSS
TBA					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Mus musculus (Mouse))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	392	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CSF1R in mouse MNFS-60 cells assessed as reduction in CSF-induced cell viability after 48 hrs by Ez-cytox reagent based assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113298 BindingDB Entry DOI: 10.7270/Q2GX4GB2
TBA					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal GST-tagged CSF1R (unknown origin) (547 to 980 residues) expressed in baculovirus infected Sf9 cells using biotin-EAIYAPFAKKK...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113298 BindingDB Entry DOI: 10.7270/Q2GX4GB2
TBA					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01571 BindingDB Entry DOI: 10.7270/Q25H7MBX
TBA					More data for this Ligand-Target Pair

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