BDBM323806 US10189809, Compound I-1

SMILES: Fc1ccccc1Cn1nc(cc1-c1ccccn1)-c1ccccn1

InChI Key: InChIKey=RBELPJXFLWVNDS-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 323806   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Guanylate cyclase soluble subunit alpha-1 (Homo sapiens (Human))	BDBM323806 (US10189809, Compound I-1) Show SMILES Fc1ccccc1Cn1nc(cc1-c1ccccn1)-c1ccccn1 Show InChI InChI=1S/C20H15FN4/c21-16-8-2-1-7-15(16)14-25-20(18-10-4-6-12-23-18)13-19(24-25)17-9-3-5-11-22-17/h1-13H,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a
Ironwood Pharmaceuticals, Inc. US Patent					Assay Description Human embryonic kidney cells (HEK293), endogenously expressing soluble guanylate cyclase (sGC), were used to evaluate the activity of test compounds....				US Patent US10189809 (2019) BindingDB Entry DOI: 10.7270/Q27H1MQ6
					More data for this Ligand-Target Pair