BindingDB logo
myBDB logout

null

SMILES: Clc1cccc(NC(=O)c2ccno2)c1N1CCN(CC=C)CC1

InChI Key: InChIKey=DZSWJFCIVCZRGJ-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 32479   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Isoform Alpha-1 of Mitogen-activated protein kinase 10 (Alpha-1) 9-402]


(Homo sapiens (Human))		BDBM32479
PNG
(piperazine amide, 6f)
Show SMILES Clc1cccc(NC(=O)c2ccno2)c1N1CCN(CC=C)CC1
Show InChI InChI=1S/C17H19ClN4O2/c1-2-8-21-9-11-22(12-10-21)16-13(18)4-3-5-14(16)20-17(23)15-6-7-19-24-15/h2-7H,1,8-12H2,(H,20,23)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.00E+3n/an/an/an/a7.022



The Scripps Research Institute



Assay Description
Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...

Bioorg Med Chem Lett 19: 3344-7 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.086
BindingDB Entry DOI: 10.7270/Q2ST7N67
More data for this
Ligand-Target Pair