BDBM325574 6-Chloro-8-[5-(1-cyclobutyl-piperidin-4-yl)-[1,3,4]oxadiazol-2-yl]-chroman-5-ylamine::US9636335, 14

SMILES: Nc1c(Cl)cc(-c2nnc(o2)C2CCN(CC2)C2CCC2)c2OCCCc12

InChI Key: InChIKey=JXDHEGNLQLKXOB-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 325574   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM325574 (6-Chloro-8-[5-(1-cyclobutyl-piperidin-4-yl)-[1,3,4...) Show SMILES Nc1c(Cl)cc(-c2nnc(o2)C2CCN(CC2)C2CCC2)c2OCCCc12 Show InChI InChI=1S/C20H25ClN4O2/c21-16-11-15(18-14(17(16)22)5-2-10-26-18)20-24-23-19(27-20)12-6-8-25(9-7-12)13-3-1-4-13/h11-13H,1-10,22H2	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
SUVEN LIFE SCIENCES LIMITED US Patent					Assay Description A stable CHO cell line expressing recombinant human 5-HT4 receptor and pCRE-Luc reporter system was used for cell-based assay. The assay offers a non...				US Patent US9636335 (2017) BindingDB Entry DOI: 10.7270/Q2PG1TTQ
					More data for this Ligand-Target Pair