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BDBM325582 6-Chloro-8-[5-(3-isopropyl-3-aza-bicyclo[3.1.0]hex-6-yl)-[1,3,4]oxadiazol-2-yl]-chroman-5-ylamine ::US9636335, 22

SMILES: CC(C)N1CC2C(C1)C2c1nnc(o1)-c1cc(Cl)c(N)c2CCCOc12

InChI Key: InChIKey=MRTFYVURPRQOTD-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 325582   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serotonin (5-HT) receptor


(Homo sapiens (Human))		BDBM325582
PNG
(6-Chloro-8-[5-(3-isopropyl-3-aza-bicyclo[3.1.0]hex...)
Show SMILES CC(C)N1CC2C(C1)C2c1nnc(o1)-c1cc(Cl)c(N)c2CCCOc12
Show InChI InChI=1S/C19H23ClN4O2/c1-9(2)24-7-12-13(8-24)15(12)19-23-22-18(26-19)11-6-14(20)16(21)10-4-3-5-25-17(10)11/h6,9,12-13,15H,3-5,7-8,21H2,1-2H3
UniProtKB/SwissProt
UniProtKB/TrEMBL

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US Patent
n/an/an/an/a 48n/an/an/an/a



SUVEN LIFE SCIENCES LIMITED

US Patent


Assay Description
A stable CHO cell line expressing recombinant human 5-HT4 receptor and pCRE-Luc reporter system was used for cell-based assay. The assay offers a non...

US Patent US9636335 (2017)


BindingDB Entry DOI: 10.7270/Q2PG1TTQ
More data for this
Ligand-Target Pair