BDBM325742 (rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]-1-morpholino-ethanone::US9636338, 16

SMILES: Fc1cc(ccc1C(F)(F)F)-c1cncc2CCC(CC(=O)N3CCOCC3)c12

InChI Key: InChIKey=ZBGYDQQWZZZKHK-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 325742   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM325742 ((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...) Show SMILES Fc1cc(ccc1C(F)(F)F)-c1cncc2CCC(CC(=O)N3CCOCC3)c12 Show InChI InChI=1S/C21H20F4N2O2/c22-18-9-13(3-4-17(18)21(23,24)25)16-12-26-11-15-2-1-14(20(15)16)10-19(28)27-5-7-29-8-6-27/h3-4,9,11-12,14H,1-2,5-8,10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...				US Patent US9636338 (2017) BindingDB Entry DOI: 10.7270/Q2988938
					More data for this Ligand-Target Pair
Cytochrome P450 11B1 (Homo sapiens (Human))	BDBM325742 ((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...) Show SMILES Fc1cc(ccc1C(F)(F)F)-c1cncc2CCC(CC(=O)N3CCOCC3)c12 Show InChI InChI=1S/C21H20F4N2O2/c22-18-9-13(3-4-17(18)21(23,24)25)16-12-26-11-15-2-1-14(20(15)16)10-19(28)27-5-7-29-8-6-27/h3-4,9,11-12,14H,1-2,5-8,10H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.63E+3	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...				US Patent US9636338 (2017) BindingDB Entry DOI: 10.7270/Q2988938
					More data for this Ligand-Target Pair