null

SMILES: CCN(C)C(=O)CC1CCc2cncc(c12)-c1ccc(cc1F)C(F)(F)F

InChI Key: InChIKey=TUXMJNRBRICPNR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 325746   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM325746 ((rac)-N-Ethyl-2-[4-[2-fluoro-4-(trifluoromethyl)ph...) Show SMILES CCN(C)C(=O)CC1CCc2cncc(c12)-c1ccc(cc1F)C(F)(F)F Show InChI InChI=1S/C20H20F4N2O/c1-3-26(2)18(27)8-12-4-5-13-10-25-11-16(19(12)13)15-7-6-14(9-17(15)21)20(22,23)24/h6-7,9-12H,3-5,8H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	213	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...				US Patent US9636338 (2017) BindingDB Entry DOI: 10.7270/Q2988938
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM325746 ((rac)-N-Ethyl-2-[4-[2-fluoro-4-(trifluoromethyl)ph...) Show SMILES CCN(C)C(=O)CC1CCc2cncc(c12)-c1ccc(cc1F)C(F)(F)F Show InChI InChI=1S/C20H20F4N2O/c1-3-26(2)18(27)8-12-4-5-13-10-25-11-16(19(12)13)15-7-6-14(9-17(15)21)20(22,23)24/h6-7,9-12H,3-5,8H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...				US Patent US9636338 (2017) BindingDB Entry DOI: 10.7270/Q2988938
					More data for this Ligand-Target Pair