BDBM32577 ent-PS-1
SMILES: CN[C@H](C)C(=O)N[C@H](C1CCOCC1)C(=O)N1CCC[C@@H]1c1nc2c(nccc2s1)-c1ccccc1Cl
InChI Key: InChIKey=AVQIBLHJFPCFMB-BSLALVQMSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cIAP-1 BIR3 (Homo sapiens (Human)) | BDBM32577 (ent-PS-1) | B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | >3.40E+4 | >-6.03 | n/a | n/a | n/a | n/a | n/a | 7.2 | 22 |
Genentech | Assay Description Samples for fluorescence polarization affinity measurements were prepared by addition of serial dilutions of target protein to each well containing a... | ACS Chem Biol 4: 557-66 (2009) Article DOI: 10.1021/cb900083m BindingDB Entry DOI: 10.7270/Q2DJ5D0Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
XIAP-BIR3 (Homo sapiens (Human)) | BDBM32577 (ent-PS-1) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | >3.40E+4 | >-6.03 | n/a | n/a | n/a | n/a | n/a | 7.2 | 22 |
Genentech | Assay Description Samples for fluorescence polarization affinity measurements were prepared by addition of serial dilutions of target protein to each well containing a... | ACS Chem Biol 4: 557-66 (2009) Article DOI: 10.1021/cb900083m BindingDB Entry DOI: 10.7270/Q2DJ5D0Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cIAP-2 BIR3 (Homo sapiens (Human)) | BDBM32577 (ent-PS-1) | B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | >3.40E+4 | >-6.03 | n/a | n/a | n/a | n/a | n/a | 7.2 | 22 |
Genentech | Assay Description Samples for fluorescence polarization affinity measurements were prepared by addition of serial dilutions of target protein to each well containing a... | ACS Chem Biol 4: 557-66 (2009) Article DOI: 10.1021/cb900083m BindingDB Entry DOI: 10.7270/Q2DJ5D0Q | |||||||||||
More data for this Ligand-Target Pair |