BDBM326393 (1R,2S)-2-[(2R)-3-Amino-2-methylpropyl]-1-[1-(5-methylpyridin-2-yl)-1H-imidazol-4-yl]cyclopropanecarboxylic acid::US9662310, Example 58

SMILES: C[C@@H](CN)C[C@H]1C[C@]1(C(O)=O)c1cn(cn1)-c1ccc(C)cn1

InChI Key: InChIKey=AAEAYCWJPQORII-IIYDPXPESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 326393   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carboxypeptidase B2 isoform A (Homo sapiens (Human))	BDBM326393 ((1R,2S)-2-[(2R)-3-Amino-2-methylpropyl]-1-[1-(5-me...) Show SMILES C[C@@H](CN)C[C@H]1C[C@]1(C(O)=O)c1cn(cn1)-c1ccc(C)cn1 |r| Show InChI InChI=1S/C17H22N4O2/c1-11-3-4-15(19-8-11)21-9-14(20-10-21)17(16(22)23)6-13(17)5-12(2)7-18/h3-4,8-10,12-13H,5-7,18H2,1-2H3,(H,22,23)/t12-,13+,17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
DAIICHI SANKYO COMPANY, LIMITED US Patent					Assay Description HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...				US Patent US9662310 (2017) BindingDB Entry DOI: 10.7270/Q2W09829
					More data for this Ligand-Target Pair