BDBM326947 1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benzyl}-2- methylpiperidine::US9662339, 68
SMILES: CC1CCCCN1Cc1ccc(cc1)[C@H]1COc2ccccc2O1
InChI Key: InChIKey=PIXMXLKELWWJLV-CAWMZFRYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leukotriene A4 hydrolase (Homo sapiens (Human)) | BDBM326947 (1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ... | US Patent US9662339 (2017) BindingDB Entry DOI: 10.7270/Q2GT5Q8D | |||||||||||
More data for this Ligand-Target Pair |