null
SMILES: NC(=O)c1nnc2CN(Cc3ccc(cc3)[C@H]3COc4cccnc4O3)CCn12
InChI Key: InChIKey=VRSIRTPCSWRLHZ-MRXNPFEDSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM327158 (7-[(S)-4-(2,3-Dihydro- [1,4]dioxino[2,3-b]pyridin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ... | US Patent US9662339 (2017) BindingDB Entry DOI: 10.7270/Q2GT5Q8D | |||||||||||
More data for this Ligand-Target Pair |