BDBM3283 4-(Benzylamino)quinazoline deriv. 34::N-benzyl-7-methoxyquinazolin-4-amine

SMILES: COc1ccc2c(NCc3ccccc3)ncnc2c1

InChI Key: InChIKey=WVKPEHVWDHASND-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3283   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3283 (4-(Benzylamino)quinazoline deriv. 34 | N-benzyl-7-...) Show SMILES COc1ccc2c(NCc3ccccc3)ncnc2c1 Show InChI InChI=1S/C16H15N3O/c1-20-13-7-8-14-15(9-13)18-11-19-16(14)17-10-12-5-3-2-4-6-12/h2-9,11H,10H2,1H3,(H,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 38: 3482-7 (1995) Article DOI: 10.1021/jm00018a008 BindingDB Entry DOI: 10.7270/Q2319T3K
					More data for this Ligand-Target Pair