BDBM328362 1-((4-methoxy-3-(4-methylpiperazin-1-yl)phenyl)sulfonyl)-1H-indole-3-carbonitrile::US9663498, Example 2

SMILES: COc1ccc(cc1N1CCN(C)CC1)S(=O)(=O)n1cc(C#N)c2ccccc12

InChI Key: InChIKey=RGAHPZKGWMVENE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328362   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM328362 (1-((4-methoxy-3-(4-methylpiperazin-1-yl)phenyl)sul...) Show SMILES COc1ccc(cc1N1CCN(C)CC1)S(=O)(=O)n1cc(C#N)c2ccccc12 Show InChI InChI=1S/C21H22N4O3S/c1-23-9-11-24(12-10-23)20-13-17(7-8-21(20)28-2)29(26,27)25-15-16(14-22)18-5-3-4-6-19(18)25/h3-8,13,15H,9-12H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.590	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...				US Patent US9663498 (2017) BindingDB Entry DOI: 10.7270/Q22N54C8
					More data for this Ligand-Target Pair