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SMILES: COc1ccc(cc1N1CCNCC1)S(=O)(=O)n1cc(C(F)F)c2cc(Cl)ccc12

InChI Key: InChIKey=OXGVSDGHNOTTRV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328385   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))		BDBM328385
PNG
(5-chloro-3-(difluoromethyl)-1-((4-methoxy-3-(piper...)
Show SMILES COc1ccc(cc1N1CCNCC1)S(=O)(=O)n1cc(C(F)F)c2cc(Cl)ccc12
Show InChI InChI=1S/C20H20ClF2N3O3S/c1-29-19-5-3-14(11-18(19)25-8-6-24-7-9-25)30(27,28)26-12-16(20(22)23)15-10-13(21)2-4-17(15)26/h2-5,10-12,20,24H,6-9H2,1H3
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PC cid
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US Patent
n/an/a 0.640n/an/an/an/an/an/a



SUNSHINE LAKE PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...

US Patent US9663498 (2017)


BindingDB Entry DOI: 10.7270/Q22N54C8
More data for this
Ligand-Target Pair