BDBM329427 5-(3-ethoxyphenyl)-2- methyl-6-(((1S,2S)-2- (quinolin-2- yl)cyclopropyl)methoxy) pyrimidin-1-ium 2,2,2- trifluoroacetate (enantiomer A)::US9663513, 40::US9663513, 41

SMILES: CCOc1cccc(c1)-c1cnc(C)[nH+]c1OC[C@H]1C[C@@H]1c1ccc2ccccc2n1

InChI Key: InChIKey=GWOCNAQGMAATMQ-IRLDBZIGSA-O

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 329427   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM329427 (5-(3-ethoxyphenyl)-2- methyl-6-(((1S,2S)-2- (quino...) Show SMILES CCOc1cccc(c1)-c1cnc(C)[nH+]c1OC[C@H]1C[C@@H]1c1ccc2ccccc2n1 |r| Show InChI InChI=1S/C26H25N3O2/c1-3-30-21-9-6-8-19(13-21)23-15-27-17(2)28-26(23)31-16-20-14-22(20)25-12-11-18-7-4-5-10-24(18)29-25/h4-13,15,20,22H,3,14,16H2,1-2H3/p+1/t20-,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...				US Patent US9663513 (2017) BindingDB Entry DOI: 10.7270/Q25D8TXC
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM329427 (5-(3-ethoxyphenyl)-2- methyl-6-(((1S,2S)-2- (quino...) Show SMILES CCOc1cccc(c1)-c1cnc(C)[nH+]c1OC[C@H]1C[C@@H]1c1ccc2ccccc2n1 |r| Show InChI InChI=1S/C26H25N3O2/c1-3-30-21-9-6-8-19(13-21)23-15-27-17(2)28-26(23)31-16-20-14-22(20)25-12-11-18-7-4-5-10-24(18)29-25/h4-13,15,20,22H,3,14,16H2,1-2H3/p+1/t20-,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.08	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...				US Patent US9663513 (2017) BindingDB Entry DOI: 10.7270/Q25D8TXC
					More data for this Ligand-Target Pair