BDBM330041 (4R,12aS)-N-(1-(2,4-difluorophenyl)cyclopropyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-9-carboxamide::US10689399, Compound 5::US9663528, 5

SMILES: C[C@@H]1CCO[C@H]2Cn3cc(C(=O)NC4(CC4)c4ccc(F)cc4F)c(=O)c(O)c3C(=O)N12

InChI Key: InChIKey=LRWVNSNSOHQKNO-BZNIZROVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330041   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
POU domain, class 2, transcription factor 2 (Homo sapiens (Human))	BDBM330041 ( (4R,12aS)-N-(1-(2,4-difluorophenyl)cyclopropyl)-7...) Show SMILES C[C@@H]1CCO[C@H]2Cn3cc(C(=O)NC4(CC4)c4ccc(F)cc4F)c(=O)c(O)c3C(=O)N12 Show InChI InChI=1S/C22H21F2N3O5/c1-11-4-7-32-16-10-26-9-13(18(28)19(29)17(26)21(31)27(11)16)20(30)25-22(5-6-22)14-3-2-12(23)8-15(14)24/h2-3,8-9,11,16,29H,4-7,10H2,1H3,(H,25,30)/t11-,16+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...				US Patent US10689399 (2020)
					More data for this Ligand-Target Pair
Solute carrier family 22 member 2 (Homo sapiens (Human))	BDBM330041 ( (4R,12aS)-N-(1-(2,4-difluorophenyl)cyclopropyl)-7...) Show SMILES C[C@@H]1CCO[C@H]2Cn3cc(C(=O)NC4(CC4)c4ccc(F)cc4F)c(=O)c(O)c3C(=O)N12 Show InChI InChI=1S/C22H21F2N3O5/c1-11-4-7-32-16-10-26-9-13(18(28)19(29)17(26)21(31)27(11)16)20(30)25-22(5-6-22)14-3-2-12(23)8-15(14)24/h2-3,8-9,11,16,29H,4-7,10H2,1H3,(H,25,30)/t11-,16+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...				US Patent US9663528 (2017) BindingDB Entry DOI: 10.7270/Q24F1SVF
					More data for this Ligand-Target Pair