BDBM330184 2-Cyclopropyl-N-[4-[[(1S,4S)-5-oxa-2-azabicyclo[2.2.1]heptan-4-yl]methyl]phenyl]pyrimidine-5-carboxamide::US9663530, Example 28

SMILES: O=C(Nc1ccc(C[C@]23CN[C@H](CO2)C3)cc1)c1cnc(nc1)C1CC1

InChI Key: InChIKey=PSULPVFIYUAPSX-PXNSSMCTSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330184   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trace amine-associated receptor 1 (TAAR1) (Rattus norvegicus (Rat))	BDBM330184 (2-Cyclopropyl-N-[4-[[(1S,4S)-5-oxa-2-azabicyclo[2....) Show SMILES O=C(Nc1ccc(C[C@]23CN[C@H](CO2)C3)cc1)c1cnc(nc1)C1CC1 |r| Show InChI InChI=1S/C20H22N4O2/c25-19(15-9-21-18(22-10-15)14-3-4-14)24-16-5-1-13(2-6-16)7-20-8-17(11-26-20)23-12-20/h1-2,5-6,9-10,14,17,23H,3-4,7-8,11-12H2,(H,24,25)/t17-,20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1) (Mus musculus (Mouse))	BDBM330184 (2-Cyclopropyl-N-[4-[[(1S,4S)-5-oxa-2-azabicyclo[2....) Show SMILES O=C(Nc1ccc(C[C@]23CN[C@H](CO2)C3)cc1)c1cnc(nc1)C1CC1 |r| Show InChI InChI=1S/C20H22N4O2/c25-19(15-9-21-18(22-10-15)14-3-4-14)24-16-5-1-13(2-6-16)7-20-8-17(11-26-20)23-12-20/h1-2,5-6,9-10,14,17,23H,3-4,7-8,11-12H2,(H,24,25)/t17-,20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair