BDBM330186 5-Chloro-N-[4-[[(1S,4S)-5-oxa-2-azabicyclo[2.2.1]heptan-4-yl]methyl]phenyl]pyridin-2-amine::US9663530, Example 30

SMILES: Clc1ccc(Nc2ccc(C[C@]34CN[C@H](CO3)C4)cc2)nc1

InChI Key: InChIKey=YCSXPCROXXBQFF-RDJZCZTQSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330186   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM330186 (5-Chloro-N-[4-[[(1S,4S)-5-oxa-2-azabicyclo[2.2.1]h...) Show SMILES Clc1ccc(Nc2ccc(C[C@]34CN[C@H](CO3)C4)cc2)nc1 |r| Show InChI InChI=1S/C17H18ClN3O/c18-13-3-6-16(19-9-13)21-14-4-1-12(2-5-14)7-17-8-15(10-22-17)20-11-17/h1-6,9,15,20H,7-8,10-11H2,(H,19,21)/t15-,17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	621	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330186 (5-Chloro-N-[4-[[(1S,4S)-5-oxa-2-azabicyclo[2.2.1]h...) Show SMILES Clc1ccc(Nc2ccc(C[C@]34CN[C@H](CO3)C4)cc2)nc1 |r| Show InChI InChI=1S/C17H18ClN3O/c18-13-3-6-16(19-9-13)21-14-4-1-12(2-5-14)7-17-8-15(10-22-17)20-11-17/h1-6,9,15,20H,7-8,10-11H2,(H,19,21)/t15-,17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair