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SMILES: FC(F)(F)c1nccc(Nc2ccc(cc2)C23CCC(CO2)NC3)n1

InChI Key: InChIKey=SYBKSRDFRQCMIY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330192   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM330192 (N-[4-(5-Oxa-2-azabicyclo[2.2.2]octan-4-yl)phenyl]-...) Show SMILES FC(F)(F)c1nccc(Nc2ccc(cc2)C23CCC(CO2)NC3)n1 Show InChI InChI=1S/C17H17F3N4O/c18-17(19,20)15-21-8-6-14(24-15)23-12-3-1-11(2-4-12)16-7-5-13(9-25-16)22-10-16/h1-4,6,8,13,22H,5,7,9-10H2,(H,21,23,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330192 (N-[4-(5-Oxa-2-azabicyclo[2.2.2]octan-4-yl)phenyl]-...) Show SMILES FC(F)(F)c1nccc(Nc2ccc(cc2)C23CCC(CO2)NC3)n1 Show InChI InChI=1S/C17H17F3N4O/c18-17(19,20)15-21-8-6-14(24-15)23-12-3-1-11(2-4-12)16-7-5-13(9-25-16)22-10-16/h1-4,6,8,13,22H,5,7,9-10H2,(H,21,23,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	47.1	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair