BDBM330397 US9725436, Entry 16
SMILES: Fc1cc(Cn2ccnc2)cc(\C=C\c2ccc(cc2)N2CCN(CC2)S(=O)(=O)C[N+]#[C-])c1
InChI Key: InChIKey=TZXSYFKSVMSTCF-NSCUHMNNSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450-C17 (CYP17A1) (Bos taurus (Bovine)) | BDBM330397 (US9725436, Entry 16) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
CORTENDO AB (PUBL) US Patent | Assay Description Cyp17 assay protocol: AD293 cells that stably over-express recombinant CYP-17 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe... | US Patent US9725436 (2017) BindingDB Entry DOI: 10.7270/Q2KD211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450-C17 (CYP17A1) (Bos taurus (Bovine)) | BDBM330397 (US9725436, Entry 16) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CORTENDO AB (PUBL) US Patent | Assay Description Cyp21 assay protocol: AD293 cells that stably over-express recombinant CYP-21 were seeded in 96 well plates coated with poly D-lysine (10,000 cell pe... | US Patent US9725436 (2017) BindingDB Entry DOI: 10.7270/Q2KD211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11A1 (CYP11A1) (Bos taurus (Bovine)) | BDBM330397 (US9725436, Entry 16) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
CORTENDO AB (PUBL) US Patent | Assay Description Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe... | US Patent US9725436 (2017) BindingDB Entry DOI: 10.7270/Q2KD211N | |||||||||||
More data for this Ligand-Target Pair |