BDBM33110 5-[(6-Bromo-2-hydroxy-naphthalen-1-ylmethylene)-amino]-1,3-dihydro-benzoimidazol-2-one::5-[[(E)-(6-bromo-2-keto-1-naphthylidene)methyl]amino]-1,3-dihydrobenzimidazol-2-one::5-[[(Z)-(6-bromanyl-2-oxidanylidene-naphthalen-1-ylidene)methyl]amino]-1,3-dihydrobenzimidazol-2-one::5-[[(Z)-(6-bromo-2-keto-1-naphthylidene)methyl]amino]-1,3-dihydrobenzimidazol-2-one::5-[[(Z)-(6-bromo-2-oxo-1-naphthalenylidene)methyl]amino]-1,3-dihydrobenzimidazol-2-one::5-[[(Z)-(6-bromo-2-oxonaphthalen-1-ylidene)methyl]amino]-1,3-dihydrobenzimidazol-2-one::MLS000553451::SMR000171789::cid_5761516

SMILES: Oc1ccc2cc(Br)ccc2c1C=Nc1ccc2[nH]c(=O)[nH]c2c1

InChI Key: InChIKey=AQWGSBHYJQLIAU-UHFFFAOYSA-N

Data: 3 IC50  5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 33110   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-related protein A1 (Homo sapiens (Human))	BDBM33110 (5-[(6-Bromo-2-hydroxy-naphthalen-1-ylmethylene)-am...) Show SMILES Oc1ccc2cc(Br)ccc2c1C=Nc1ccc2[nH]c(=O)[nH]c2c1 |w:13.15| Show InChI InChI=1S/C18H12BrN3O2/c19-11-2-4-13-10(7-11)1-6-17(23)14(13)9-20-12-3-5-15-16(8-12)22-18(24)21-15/h1-9,23H,(H2,21,22,24)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	4.46E+3	n/a	n/a	7.4	4
NMMLSC Curated by PubChem BioAssay					Assay Description The multiplex is constructed by using beads for each protein target that have been labeled with varying intensities of red color, so that each assay ...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2CN728N
					More data for this Ligand-Target Pair
MPI protein (Homo sapiens (Human))	BDBM33110 (5-[(6-Bromo-2-hydroxy-naphthalen-1-ylmethylene)-am...) Show SMILES Oc1ccc2cc(Br)ccc2c1C=Nc1ccc2[nH]c(=O)[nH]c2c1 |w:13.15| Show InChI InChI=1S/C18H12BrN3O2/c19-11-2-4-13-10(7-11)1-6-17(23)14(13)9-20-12-3-5-15-16(8-12)22-18(24)21-15/h1-9,23H,(H2,21,22,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description The purpose of this assay is to identify non-competititve inhibitors of human PMI. This is accomplished by using a G6PD- NADPH-coupled assay. In the ...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2CF9NFM
					More data for this Ligand-Target Pair
BCL-W (Homo sapiens (Human))	BDBM33110 (5-[(6-Bromo-2-hydroxy-naphthalen-1-ylmethylene)-am...) Show SMILES Oc1ccc2cc(Br)ccc2c1C=Nc1ccc2[nH]c(=O)[nH]c2c1 |w:13.15| Show InChI InChI=1S/C18H12BrN3O2/c19-11-2-4-13-10(7-11)1-6-17(23)14(13)9-20-12-3-5-15-16(8-12)22-18(24)21-15/h1-9,23H,(H2,21,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	4.15E+3	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2BR8QM3
					More data for this Ligand-Target Pair
mRNA interferase toxin, antitoxin is MazE (Escherichia coli str. K-12 substr. MG1655)	BDBM33110 (5-[(6-Bromo-2-hydroxy-naphthalen-1-ylmethylene)-am...) Show SMILES Oc1ccc2cc(Br)ccc2c1C=Nc1ccc2[nH]c(=O)[nH]c2c1 |w:13.15| Show InChI InChI=1S/C18H12BrN3O2/c19-11-2-4-13-10(7-11)1-6-17(23)14(13)9-20-12-3-5-15-16(8-12)22-18(24)21-15/h1-9,23H,(H2,21,22,24)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	5.48E+3	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2TB15DB
					More data for this Ligand-Target Pair
BZLF2 (Human herpesvirus 4 type 2)	BDBM33110 (5-[(6-Bromo-2-hydroxy-naphthalen-1-ylmethylene)-am...) Show SMILES Oc1ccc2cc(Br)ccc2c1C=Nc1ccc2[nH]c(=O)[nH]c2c1 |w:13.15| Show InChI InChI=1S/C18H12BrN3O2/c19-11-2-4-13-10(7-11)1-6-17(23)14(13)9-20-12-3-5-15-16(8-12)22-18(24)21-15/h1-9,23H,(H2,21,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2057DCW
					More data for this Ligand-Target Pair
Bcl-2-related protein A1 (Homo sapiens (Human))	BDBM33110 (5-[(6-Bromo-2-hydroxy-naphthalen-1-ylmethylene)-am...) Show SMILES Oc1ccc2cc(Br)ccc2c1C=Nc1ccc2[nH]c(=O)[nH]c2c1 |w:13.15| Show InChI InChI=1S/C18H12BrN3O2/c19-11-2-4-13-10(7-11)1-6-17(23)14(13)9-20-12-3-5-15-16(8-12)22-18(24)21-15/h1-9,23H,(H2,21,22,24)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.35E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2HQ3XCR
					More data for this Ligand-Target Pair
mRNA interferase toxin, antitoxin is MazE (Escherichia coli str. K-12 substr. MG1655)	BDBM33110 (5-[(6-Bromo-2-hydroxy-naphthalen-1-ylmethylene)-am...) Show SMILES Oc1ccc2cc(Br)ccc2c1C=Nc1ccc2[nH]c(=O)[nH]c2c1 |w:13.15| Show InChI InChI=1S/C18H12BrN3O2/c19-11-2-4-13-10(7-11)1-6-17(23)14(13)9-20-12-3-5-15-16(8-12)22-18(24)21-15/h1-9,23H,(H2,21,22,24)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>9.90E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2Z31X54
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM33110 (5-[(6-Bromo-2-hydroxy-naphthalen-1-ylmethylene)-am...) Show SMILES Oc1ccc2cc(Br)ccc2c1C=Nc1ccc2[nH]c(=O)[nH]c2c1 |w:13.15| Show InChI InChI=1S/C18H12BrN3O2/c19-11-2-4-13-10(7-11)1-6-17(23)14(13)9-20-12-3-5-15-16(8-12)22-18(24)21-15/h1-9,23H,(H2,21,22,24)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q23X8539
					More data for this Ligand-Target Pair