BDBM3314 4-N-(2-methoxyphenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-Aminopyrido[4,3-d]pyrimidine 7k::7-amino-4-[(2-methoxyphenyl)amino]pyrido[4,3-d]pyrimidine

SMILES: COc1ccccc1Nc1ncnc2cc(N)ncc12

InChI Key: InChIKey=ZHZNAKBOBOUWQI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3314   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3314 (4-N-(2-methoxyphenyl)pyrido[4,3-d]pyrimidine-4,7-d...) Show SMILES COc1ccccc1Nc1ncnc2cc(N)ncc12 Show InChI InChI=1S/C14H13N5O/c1-20-12-5-3-2-4-10(12)19-14-9-7-16-13(15)6-11(9)17-8-18-14/h2-8H,1H3,(H2,15,16)(H,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.71E+3	n/a	n/a	n/a	n/a	7.4	22
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 38: 3780-8 (1995) Article DOI: 10.1021/jm00019a007 BindingDB Entry DOI: 10.7270/Q2Z899M8
					More data for this Ligand-Target Pair