BindingDB logo
myBDB logout

null

SMILES: COc1ccccc1-c1cnc(nc1)N1CC2(CC2)c2ccc(cc12)C(=O)N1CCOCC1

InChI Key: InChIKey=SWXPWTMBNQTRCC-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332079   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM332079
PNG
(US10189854, Compound 31 | [1-[5-(2-Methoxyphenyl)-...)
Show SMILES COc1ccccc1-c1cnc(nc1)N1CC2(CC2)c2ccc(cc12)C(=O)N1CCOCC1
Show InChI InChI=1S/C26H26N4O3/c1-32-23-5-3-2-4-20(23)19-15-27-25(28-16-19)30-17-26(8-9-26)21-7-6-18(14-22(21)30)24(31)29-10-12-33-13-11-29/h2-7,14-16H,8-13,17H2,1H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



GRUENENTHAL GMBH

US Patent


Assay Description
The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...

US Patent US10189854 (2019)


BindingDB Entry DOI: 10.7270/Q2N87CW4
More data for this
Ligand-Target Pair