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SMILES: O=C(N1CCOCC1)c1ccc2c(c1)N(CC21CC1)c1ncc(cn1)-c1cccc(c1)C#N

InChI Key: InChIKey=NZDBEFJVZZWMOV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332102   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM332102
PNG
(3-[2-[6-(Morpholine-4-carbonyl)-spiro[1,2-dihydro-...)
Show SMILES O=C(N1CCOCC1)c1ccc2c(c1)N(CC21CC1)c1ncc(cn1)-c1cccc(c1)C#N
Show InChI InChI=1S/C26H23N5O2/c27-14-18-2-1-3-19(12-18)21-15-28-25(29-16-21)31-17-26(6-7-26)22-5-4-20(13-23(22)31)24(32)30-8-10-33-11-9-30/h1-5,12-13,15-16H,6-11,17H2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



GRUENENTHAL GMBH

US Patent


Assay Description
The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...

US Patent US10189854 (2019)


BindingDB Entry DOI: 10.7270/Q2N87CW4
More data for this
Ligand-Target Pair