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BDBM33260 biguanidine, 2

SMILES: [#7]-[#6](=[#7])-[#7]-[#7]=[#6]-[#6]=[#7]\[#7]=[#6](\[#7])-[#7]

InChI Key: InChIKey=JCJMVSDVPRRNSU-UHFFFAOYSA-N

Data: 4 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 33260
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Trypsin (Bos taurus (bovine))	BDBM33260 (biguanidine, 2) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.55E+5	-5.16	n/a	n/a	n/a	n/a	n/a	7.6	23
University of Alabama at Birmingham					Assay Description All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...				Bioorg Med Chem 13: 257-64 (2005) Article DOI: 10.1016/j.bmc.2004.09.036 BindingDB Entry DOI: 10.7270/Q2QV3JVQ
University of Alabama at Birmingham					More data for this Ligand-Target Pair
West Nile Virus (WNV) NS2B-NS3 Protease (West Nile virus (WNV))	BDBM33260 (biguanidine, 2) Show SMILES Show InChI	PDB MMDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.37E+5	-4.70	n/a	n/a	n/a	n/a	n/a	8.5	23
University of Alabama at Birmingham					Assay Description All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...				Bioorg Med Chem 13: 257-64 (2005) Article DOI: 10.1016/j.bmc.2004.09.036 BindingDB Entry DOI: 10.7270/Q2QV3JVQ
University of Alabama at Birmingham					More data for this Ligand-Target Pair
Dengue Virus 2 (DENV2) NS2B-NS3 Protease (Dengue virus 2 (strain TSV01))	BDBM33260 (biguanidine, 2) Show SMILES Show InChI	PDB MMDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.23E+5	-4.57	n/a	n/a	n/a	n/a	n/a	8.5	23
University of Alabama at Birmingham					Assay Description All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...				Bioorg Med Chem 13: 257-64 (2005) Article DOI: 10.1016/j.bmc.2004.09.036 BindingDB Entry DOI: 10.7270/Q2QV3JVQ
University of Alabama at Birmingham					More data for this Ligand-Target Pair
Alpha-chymotrypsin (Bos taurus (bovine))	BDBM33260 (biguanidine, 2) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.35E+6	-3.89	n/a	n/a	n/a	n/a	n/a	7.6	23
University of Alabama at Birmingham					Assay Description All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...				Bioorg Med Chem 13: 257-64 (2005) Article DOI: 10.1016/j.bmc.2004.09.036 BindingDB Entry DOI: 10.7270/Q2QV3JVQ
University of Alabama at Birmingham					More data for this Ligand-Target Pair