BDBM332641 3-(4-fluorophenyl)-1-(7-{[4-(trifluoromethyl)phenyl]carbonyl}-2,7-diazaspiro[3.5]non-2-yl)prop-2-yn-1-one::US10196369, Compound C96

SMILES: Fc1ccc(cc1)C#CC(=O)N1CC2(C1)CCN(CC2)C(=O)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=DGSBQEAMRIUUTM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332641   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332641 (3-(4-fluorophenyl)-1-(7-{[4-(trifluoromethyl)pheny...) Show SMILES Fc1ccc(cc1)C#CC(=O)N1CC2(C1)CCN(CC2)C(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H20F4N2O2/c25-20-8-1-17(2-9-20)3-10-21(31)30-15-23(16-30)11-13-29(14-12-23)22(32)18-4-6-19(7-5-18)24(26,27)28/h1-2,4-9H,11-16H2	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair