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SMILES: NC(=O)c1cc(F)cc2[nH]c(nc12)N1CCN(CC1)c1cnc(cn1)C#N

InChI Key: InChIKey=UWKKGXSTZXVPNK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332747   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM332747
PNG
(2-(4-(5-cyanopyrazin-2-yl)piperazin-1-yl)-6-fluoro...)
Show SMILES NC(=O)c1cc(F)cc2[nH]c(nc12)N1CCN(CC1)c1cnc(cn1)C#N
Show InChI InChI=1S/C17H15FN8O/c18-10-5-12(16(20)27)15-13(6-10)23-17(24-15)26-3-1-25(2-4-26)14-9-21-11(7-19)8-22-14/h5-6,8-9H,1-4H2,(H2,20,27)(H,23,24)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 3n/an/an/an/an/an/a



SHANGHAI HUILUN LIFE SCIENCE &TECHNOLOGY CO., LTD

US Patent


Assay Description
1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...

US Patent US10196381 (2019)


BindingDB Entry DOI: 10.7270/Q2TT4T17
More data for this
Ligand-Target Pair