null
SMILES: Fc1cccc(F)c1-c1nc2CNC(=O)c2c(Nc2ccc(CC(=O)N3CCS(=O)(=O)CC3)cc2)n1
InChI Key: InChIKey=FKWRGYWLZPOKEE-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM332812 (US10196390, Compound I-84) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nimbus Lakshmi, Inc. US Patent | Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech... | US Patent US10196390 (2019) BindingDB Entry DOI: 10.7270/Q22809Q4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM332812 (US10196390, Compound I-84) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 55 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nimbus Lakshmi, Inc. US Patent | US Patent US10196390 (2019) BindingDB Entry DOI: 10.7270/Q22809Q4 | ||||||||||||
More data for this Ligand-Target Pair |