BDBM333021 US10196391, Example 21

SMILES: CCOc1cc(cc(F)c1F)N1CCc2nc(ncc2C1)-c1ccccn1

InChI Key: InChIKey=VCEMIBCAKMUFQD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333021   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis GB virus B NS5B RNA-dependent RNA polymerase (Hepatitis GB virus B)	BDBM333021 (US10196391, Example 21) Show SMILES CCOc1cc(cc(F)c1F)N1CCc2nc(ncc2C1)-c1ccccn1 Show InChI InChI=1S/C20H18F2N4O/c1-2-27-18-10-14(9-15(21)19(18)22)26-8-6-16-13(12-26)11-24-20(25-16)17-5-3-4-7-23-17/h3-5,7,9-11H,2,6,8,12H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	321	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...				US Patent US10196391 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HNM
					More data for this Ligand-Target Pair