BDBM333048 US10196391, Example 48

SMILES: CC1CN(Cc2cnc(nc12)-c1ccccn1)c1ccc(cc1)[N+]([O-])=O

InChI Key: InChIKey=ZHJJZWJUGUOGQE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333048   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis GB virus B NS5B RNA-dependent RNA polymerase (Hepatitis GB virus B)	BDBM333048 (US10196391, Example 48) Show SMILES CC1CN(Cc2cnc(nc12)-c1ccccn1)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C19H17N5O2/c1-13-11-23(15-5-7-16(8-6-15)24(25)26)12-14-10-21-19(22-18(13)14)17-4-2-3-9-20-17/h2-10,13H,11-12H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...				US Patent US10196391 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HNM
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