BindingDB logo
myBDB logout

null

SMILES: COc1ccnc(N2CCc3nc(ncc3C2)-c2ccccn2)c1F

InChI Key: InChIKey=DQGPAIPZYZDRBX-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333070   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein


(Hepatitis GB virus B)		BDBM333070
PNG
(6-(5-fluoro-4-methoxy-2-pyridyl)-2-(2-pyridyl)-7,8...)
Show SMILES COc1ccnc(N2CCc3nc(ncc3C2)-c2ccccn2)c1F
Show InChI InChI=1S/C18H16FN5O/c1-25-15-5-8-21-18(16(15)19)24-9-6-13-12(11-24)10-22-17(23-13)14-4-2-3-7-20-14/h2-5,7-8,10H,6,9,11H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.55E+3n/an/an/an/an/an/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...

US Patent US10196391 (2019)


BindingDB Entry DOI: 10.7270/Q2XK8HNM
More data for this
Ligand-Target Pair