BDBM333239 3-chloro-N-(3-((2S,3R,4S)-3,4-dihydroxytetrahydrothiophen-2-yl)-[1,2,4]triazolo[4,3-a]pyrazin-8-yl)benzenesulfonamide::US10196396, Compound 34

SMILES: O[C@@H]1CS[C@H]([C@@H]1O)c1nnc2c(NS(=O)(=O)c3cccc(Cl)c3)nccn12

InChI Key: InChIKey=HKPQBDKXBXPJBW-IJLUTSLNSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 333239   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A3 (Homo sapiens (Human))	BDBM333239 (3-chloro-N-(3-((2S,3R,4S)-3,4-dihydroxytetrahydrot...) Show SMILES O[C@@H]1CS[C@H]([C@@H]1O)c1nnc2c(NS(=O)(=O)c3cccc(Cl)c3)nccn12 Show InChI InChI=1S/C15H14ClN5O4S2/c16-8-2-1-3-9(6-8)27(24,25)20-13-15-19-18-14(21(15)5-4-17-13)12-11(23)10(22)7-26-12/h1-6,10-12,22-23H,7H2,(H,17,20)/t10-,11-,12-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
HANDOK INC. US Patent					Assay Description HEK-293 cell membrane homogenates (32 μg protein), in which A3 adenosine receptors were expressed, are incubated for 120 min at 22° C. with 0.15...				US Patent US10196396 (2019) BindingDB Entry DOI: 10.7270/Q2DJ5HQC
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM333239 (3-chloro-N-(3-((2S,3R,4S)-3,4-dihydroxytetrahydrot...) Show SMILES O[C@@H]1CS[C@H]([C@@H]1O)c1nnc2c(NS(=O)(=O)c3cccc(Cl)c3)nccn12 Show InChI InChI=1S/C15H14ClN5O4S2/c16-8-2-1-3-9(6-8)27(24,25)20-13-15-19-18-14(21(15)5-4-17-13)12-11(23)10(22)7-26-12/h1-6,10-12,22-23H,7H2,(H,17,20)/t10-,11-,12-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
HANDOK INC. US Patent					Assay Description HEK-293 cell membrane homogenates (32 μg protein), in which A3 adenosine receptors were expressed, are incubated for 120 min at 22° C. with 0.15...				US Patent US10196396 (2019) BindingDB Entry DOI: 10.7270/Q2DJ5HQC
					More data for this Ligand-Target Pair