BDBM333394 1-{[3-(4-Methoxyfuro[3,2-c]pyridin-2-yl)imidazo[1,2-b]pyridazin-6-yl](methyl)amino}propan-2-ol::US9730929, Example 15

SMILES: COc1cccc2oc(cc12)-c1cnc2ccc(nn12)N(C)CC(C)O

InChI Key: InChIKey=HCOHSVMQQKLAAV-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333394   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM333394 (1-{[3-(4-Methoxyfuro[3,2-c]pyridin-2-yl)imidazo[1,...) Show SMILES COc1cccc2oc(cc12)-c1cnc2ccc(nn12)N(C)CC(C)O |w:23.28| Show InChI InChI=1S/C19H20N4O3/c1-12(24)11-22(2)19-8-7-18-20-10-14(23(18)21-19)17-9-13-15(25-3)5-4-6-16(13)26-17/h4-10,12,24H,11H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...				US Patent US9730929 (2017) BindingDB Entry DOI: 10.7270/Q28S4S1H
					More data for this Ligand-Target Pair