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BDBM33418 pyrimidinol carboxylic acid, 10

SMILES: COc1ccc(Cc2nc(C(O)=O)c(O)c(=O)[nH]2)cc1Br

InChI Key: InChIKey=LQQYBZYFFRDXNT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 33418   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribonuclease H1


(Homo sapiens (Human))
BDBM33418
PNG
(pyrimidinol carboxylic acid, 10)
Show SMILES COc1ccc(Cc2nc(C(O)=O)c(O)c(=O)[nH]2)cc1Br
Show InChI InChI=1S/C13H11BrN2O5/c1-21-8-3-2-6(4-7(8)14)5-9-15-10(13(19)20)11(17)12(18)16-9/h2-4,17H,5H2,1H3,(H,19,20)(H,15,16,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.40E+4n/an/an/an/a8.020



Gilead Sciences Inc.



Assay Description
Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...


J Med Chem 52: 5781-4 (2009)

More data for this
Ligand-Target Pair
HIV-1 Reverse Transcriptase RNase H


(Human immunodeficiency virus 1)
BDBM33418
PNG
(pyrimidinol carboxylic acid, 10)
Show SMILES COc1ccc(Cc2nc(C(O)=O)c(O)c(=O)[nH]2)cc1Br
Show InChI InChI=1S/C13H11BrN2O5/c1-21-8-3-2-6(4-7(8)14)5-9-15-10(13(19)20)11(17)12(18)16-9/h2-4,17H,5H2,1H3,(H,19,20)(H,15,16,18)
PDB
MMDB

B.MOAD
DrugBank
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.15E+3n/an/an/an/a8.020



Gilead Sciences Inc.



Assay Description
Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...


J Med Chem 52: 5781-4 (2009)

More data for this
Ligand-Target Pair