BDBM3345 4-N-[(3-aminophenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine::7-Aminopyrido[4,3-d]pyrimidine 8o::7-amino-4-[[(3-aminophenyl)methyl]amino]pyrido[4,3-d]pyimidine

SMILES: Nc1cccc(CNc2ncnc3cc(N)ncc23)c1

InChI Key: InChIKey=FIDYSXSIFTWCGR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3345   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3345 (4-N-[(3-aminophenyl)methyl]pyrido[4,3-d]pyrimidine...) Show SMILES Nc1cccc(CNc2ncnc3cc(N)ncc23)c1 Show InChI InChI=1S/C14H14N6/c15-10-3-1-2-9(4-10)6-18-14-11-7-17-13(16)5-12(11)19-8-20-14/h1-5,7-8H,6,15H2,(H2,16,17)(H,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 38: 3780-8 (1995) Article DOI: 10.1021/jm00019a007 BindingDB Entry DOI: 10.7270/Q2Z899M8
					More data for this Ligand-Target Pair