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BDBM335400 (3S)-3-[5-(6-amino-2-chloro-3-pyridinyl)-1H-imidazol-2-yl]-7-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]-2,3-dihydro-5(1H)-indolizinone::US9732085, 210

SMILES: Nc1ccc(-c2cnc([nH]2)[C@@H]2CCc3cc(cc(=O)n23)-c2cc(Cl)ccc2-n2cnnn2)c(Cl)n1

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335400   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor XI


(Homo sapiens (Human))
BDBM335400
PNG
((3S)-3-[5-(6-amino-2-chloro-3-pyridinyl)-1H-imidaz...)
Show SMILES Nc1ccc(-c2cnc([nH]2)[C@@H]2CCc3cc(cc(=O)n23)-c2cc(Cl)ccc2-n2cnnn2)c(Cl)n1 |r|
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 2.80n/an/an/an/an/an/a



ONO PHARMACEUTICAL CO., LTD.

US Patent




US Patent US9732085 (2017)

More data for this
Ligand-Target Pair