BDBM336263 US9744172, Compound UNC582A

SMILES: CCCCNc1ncc2c(nn(CC3CC[C@H](N)CC3)c2n1)-c1ccc(cc1)N1CCOCC1

InChI Key: InChIKey=WUUJHWOTTCPVIY-QSNACTPISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336263   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM336263 (US9744172, Compound UNC582A) Show SMILES CCCCNc1ncc2c(nn(CC3CC[C@H](N)CC3)c2n1)-c1ccc(cc1)N1CCOCC1 |r,wD:16.16,(-8.57,-4.12,;-7.24,-3.35,;-5.91,-4.12,;-4.57,-3.35,;-3.24,-4.12,;-1.91,-3.35,;-1.91,-1.81,;-.57,-1.04,;.76,-1.81,;2.23,-1.33,;3.13,-2.58,;2.23,-3.82,;2.62,-5.31,;4.11,-5.71,;5.2,-4.62,;6.69,-5.02,;7.09,-6.51,;8.57,-6.9,;6,-7.59,;4.51,-7.2,;.76,-3.35,;-.57,-4.12,;2.62,.16,;4.11,.56,;4.51,2.04,;3.42,3.13,;1.93,2.73,;1.54,1.25,;3.82,4.62,;5.31,5.02,;5.71,6.51,;4.62,7.59,;3.13,7.2,;2.73,5.71,)| Show InChI InChI=1S/C26H37N7O/c1-2-3-12-28-26-29-17-23-24(20-6-10-22(11-7-20)32-13-15-34-16-14-32)31-33(25(23)30-26)18-19-4-8-21(27)9-5-19/h6-7,10-11,17,19,21H,2-5,8-9,12-16,18,27H2,1H3,(H,28,29,30)/t19?,21-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...				US Patent US9744172 (2017) BindingDB Entry DOI: 10.7270/Q2PR7Z30
					More data for this Ligand-Target Pair