BindingDB logo
myBDB logout

BDBM337382 US9745317, 20

SMILES: Cc1cc(Oc2ncnc3CCCc23)ccc1-c1c(C)ncnc1C

InChI Key: InChIKey=ZBFUNBKLXXAHPC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337382   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(1A) dopamine receptor


(Homo sapiens (Human))		BDBM337382
PNG
(US9745317, 20)
Show SMILES Cc1cc(Oc2ncnc3CCCc23)ccc1-c1c(C)ncnc1C |(.52,4.23,;.52,2.69,;-.82,1.92,;-.82,.38,;-2.15,-.39,;-2.15,-1.93,;-.82,-2.7,;-.82,-4.24,;-2.15,-5.01,;-3.48,-4.24,;-4.95,-4.71,;-5.85,-3.47,;-4.95,-2.22,;-3.48,-2.7,;.52,-.38,;1.85,.38,;1.85,1.92,;3.19,2.7,;3.19,4.24,;1.85,5.01,;4.52,5,;5.85,4.24,;5.85,2.7,;4.52,1.93,;4.52,.39,)|
Show InChI InChI=1S/C20H20N4O/c1-12-9-15(25-20-17-5-4-6-18(17)23-11-24-20)7-8-16(12)19-13(2)21-10-22-14(19)3/h7-11H,4-6H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 446n/an/an/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...

US Patent US9745317 (2017)


BindingDB Entry DOI: 10.7270/Q2W95CBQ
More data for this
Ligand-Target Pair