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BDBM337388 US9745317, 26

SMILES: Cc1n[nH]c(=O)c(C)c1-c1ccc(Oc2nccc3OCCc23)cc1C#N

InChI Key: InChIKey=OVPWTXZFXSLPPC-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337388   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(1A) dopamine receptor


(Homo sapiens (Human))		BDBM337388
PNG
(US9745317, 26)
Show SMILES Cc1n[nH]c(=O)c(C)c1-c1ccc(Oc2nccc3OCCc23)cc1C#N |(4.52,-.38,;4.52,1.16,;5.85,1.93,;5.85,3.47,;4.52,4.23,;4.52,5.78,;3.19,3.47,;1.85,4.24,;3.19,1.93,;1.85,1.15,;1.85,-.38,;.52,-1.15,;-.82,-.38,;-2.15,-1.15,;-2.15,-2.69,;-.82,-3.47,;-.82,-5,;-2.15,-5.78,;-3.48,-5,;-4.95,-5.48,;-5.85,-4.23,;-4.95,-2.99,;-3.48,-3.47,;-.82,1.15,;.52,1.98,;.52,3.52,;.52,5.06,)|
Show InChI InChI=1S/C20H16N4O3/c1-11-18(12(2)23-24-19(11)25)15-4-3-14(9-13(15)10-21)27-20-16-6-8-26-17(16)5-7-22-20/h3-5,7,9H,6,8H2,1-2H3,(H,24,25)
PDB

KEGG

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PC cid
PC sid
UniChem
US Patent
 162n/an/an/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...

US Patent US9745317 (2017)


BindingDB Entry DOI: 10.7270/Q2W95CBQ
More data for this
Ligand-Target Pair