BDBM33932 4-(3H-1,3-benzothiazol-2-ylidene)-1-cyclohexa-2,5-dienone::4-(3H-1,3-benzothiazol-2-ylidene)cyclohexa-2,5-dien-1-one::CHEMBL47875::MLS000773814::SMR000364661::cid_5351155

SMILES: Oc1ccc(cc1)-c1nc2ccccc2s1

InChI Key: InChIKey=ODMDLCWSMSFWCW-UHFFFAOYSA-N

Data: 2 KI  3 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 33932   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM33932 (4-(3H-1,3-benzothiazol-2-ylidene)-1-cyclohexa-2,5-...) Show SMILES Oc1ccc(cc1)-c1nc2ccccc2s1 Show InChI InChI=1S/C13H9NOS/c15-10-7-5-9(6-8-10)13-14-11-3-1-2-4-12(11)16-13/h1-8,15H	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	567	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pusan National University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase at 1.25 uM by Lineweaver-burk plot analysis				Bioorg Med Chem Lett 21: 2445-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.064 BindingDB Entry DOI: 10.7270/Q2PN95XZ
					More data for this Ligand-Target Pair
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM33932 (4-(3H-1,3-benzothiazol-2-ylidene)-1-cyclohexa-2,5-...) Show SMILES Oc1ccc(cc1)-c1nc2ccccc2s1 Show InChI InChI=1S/C13H9NOS/c15-10-7-5-9(6-8-10)13-14-11-3-1-2-4-12(11)16-13/h1-8,15H	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pusan National University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase at 20 uM by Lineweaver-burk plot analysis				Bioorg Med Chem Lett 21: 2445-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.064 BindingDB Entry DOI: 10.7270/Q2PN95XZ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM33932 (4-(3H-1,3-benzothiazol-2-ylidene)-1-cyclohexa-2,5-...) Show SMILES Oc1ccc(cc1)-c1nc2ccccc2s1 Show InChI InChI=1S/C13H9NOS/c15-10-7-5-9(6-8-10)13-14-11-3-1-2-4-12(11)16-13/h1-8,15H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta glucuronidase assessed as p-nitrophenol formation after 30 mins by spectrophotometric method				Bioorg Med Chem 19: 4286-94 (2011) Article DOI: 10.1016/j.bmc.2011.05.052 BindingDB Entry DOI: 10.7270/Q2FB55SC
					More data for this Ligand-Target Pair
tumor necrosis factor receptor superfamily member 10B isoform 1 precursor [Homo sapiens] (Homo sapiens (Human))	BDBM33932 (4-(3H-1,3-benzothiazol-2-ylidene)-1-cyclohexa-2,5-...) Show SMILES Oc1ccc(cc1)-c1nc2ccccc2s1 Show InChI InChI=1S/C13H9NOS/c15-10-7-5-9(6-8-10)13-14-11-3-1-2-4-12(11)16-13/h1-8,15H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay									PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2P55M4P
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM33932 (4-(3H-1,3-benzothiazol-2-ylidene)-1-cyclohexa-2,5-...) Show SMILES Oc1ccc(cc1)-c1nc2ccccc2s1 Show InChI InChI=1S/C13H9NOS/c15-10-7-5-9(6-8-10)13-14-11-3-1-2-4-12(11)16-13/h1-8,15H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	7.5	23
PCMD Curated by PubChem BioAssay					Assay Description HTS was performed using 217,350 compounds of the MLSCN library individually plated into 10ul 1536 compound plates at a concentration of 2.5 mM each, ...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2K64GDN
					More data for this Ligand-Target Pair
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM33932 (4-(3H-1,3-benzothiazol-2-ylidene)-1-cyclohexa-2,5-...) Show SMILES Oc1ccc(cc1)-c1nc2ccccc2s1 Show InChI InChI=1S/C13H9NOS/c15-10-7-5-9(6-8-10)13-14-11-3-1-2-4-12(11)16-13/h1-8,15H	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pusan National University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using L-tyrosine as a substrate				Bioorg Med Chem Lett 21: 2445-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.064 BindingDB Entry DOI: 10.7270/Q2PN95XZ
					More data for this Ligand-Target Pair