BDBM340867 US9765054, Compound 25D::US9765054, Compound 28d

SMILES: ONC(=O)[C@@H]1[C@@H]([C@H]1c1ccnc(c1)C1CC1)c1ccc(F)cc1

InChI Key: InChIKey=ZVRAEVJPHJQADI-BRWVUGGUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 340867   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 4 (Homo sapiens (Human))	BDBM340867 (US9765054, Compound 25D | US9765054, Compound 28d) Show SMILES ONC(=O)[C@@H]1[C@@H]([C@H]1c1ccnc(c1)C1CC1)c1ccc(F)cc1 Show InChI InChI=1S/C18H17FN2O2/c19-13-5-3-11(4-6-13)15-16(17(15)18(22)21-23)12-7-8-20-14(9-12)10-1-2-10/h3-10,15-17,23H,1-2H2,(H,21,22)/t15-,16-,17-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description 5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the...				US Patent US9765054 (2017) BindingDB Entry DOI: 10.7270/Q2XW4MZG
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM340867 (US9765054, Compound 25D | US9765054, Compound 28d) Show SMILES ONC(=O)[C@@H]1[C@@H]([C@H]1c1ccnc(c1)C1CC1)c1ccc(F)cc1 Show InChI InChI=1S/C18H17FN2O2/c19-13-5-3-11(4-6-13)15-16(17(15)18(22)21-23)12-7-8-20-14(9-12)10-1-2-10/h3-10,15-17,23H,1-2H2,(H,21,22)/t15-,16-,17-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description 5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the...				US Patent US9765054 (2017) BindingDB Entry DOI: 10.7270/Q2XW4MZG
					More data for this Ligand-Target Pair